Cardiac Model Based Approach to QT Estimation

Authors

Richard J. Povinelli, Marquette UniversityFollow
Mohamed A. Mneimneh, Retail Supply Network
Michael T. Johnson, Marquette UniversityFollow

Document Type

Conference Proceeding

Language

eng

Format of Original

4 p.

Publication Date

9-17-2006

Publisher

Institute of Electrical and Electronics Engineers

Source Publication

Computers in Cardiology, 2006

Source ISSN

978-1-4244-2532-7

Abstract

Because the direction of regulatory agencies requires the study of potential proarrhythmic side effects of drugs be conducted by skilled readers, the 2006 Physio-net/Computers in Cardiology Challenge focuses on the need for clinically acceptable automatic measurement of the QT duration. This entry to the challenge approaches the problem from an inverse ECG perspective. The model parameters are estimated through the minimization of the squared error between the generated ECG signal from the activity of the AV node, endocardium and epicardium, and the recorded ECG. The PQ junction and the end of the T wave are determined from the activation and deactivation of the ventricular activity. This approach is tested on the PTB Diagnostic ECG Database, which contains 549 records from 294 subjects. The final score for this method was substantially improved from 130.70 ms to 51.69 ms as compared to the best score of 17.33 ms for automatic methods.

Comments

Accepted version. Published as part of the proceedings of the conference, Computers in Cardiology, 2006: 333-336. Publisher link. © 2006 Institute of Electrical and Electronic Engineers (IEEE). Used with permission.

Recommended Citation

Povinelli, Richard J.; Mneimneh, Mohamed A.; and Johnson, Michael T., "Cardiac Model Based Approach to QT Estimation" (2006). Electrical and Computer Engineering Faculty Research and Publications. 114.
https://epublications.marquette.edu/electric_fac/114