Brain-Spinal Feedforward–Feedback Interactions Affect Output Pattern and Intracellular Properties of Motor Networks in the Lamprey
Format of Original
In many vertebrates locomotor-like activity can be induced from spinal neurons. The effects of supraspinal input on this spinal rhythm are not well understood. Using an in vitro lamprey preparation we find that in the presence of the brain–spinal cord feedforward–feedback loop the ability of the spinal circuits to produce fictive locomotion is altered. Also, the variability in the cycle period and intersegmental delay increased. We have developed novel signal processing techniques utilizing wavelet decomposition and time-varying covariance to analyze the neural activity. We suggest that the brain–spinal cord system should be viewed as a single dynamical system capable of multiple behavioral states.