Document Type

Article

Language

eng

Publication Date

4-24-2012

Publisher

Elsevier

Source Publication

Current Biology

Source ISSN

0960-9822

Abstract

Multicellular animals are a diverse lot, with widely varied body plans and lifestyles. One feature they share, however, is a nearly universal reliance on sexual reproduction for species propagation. Humans have long been fascinated by human sex differences and formal theories on how human sex is determined date at least to Aristotle (in De Generatione Animalium, ca. 335 BCE). However, it is only in the past couple of decades that the genetic and molecular programs responsible for generating the two sexes have been understood in any detail. Sex, it turns out, can be established by many very different and fast-evolving mechanisms, but often these involve a conserved class of transcriptional regulators, the DM domain proteins.

Comments

Accepted version. Current Biology, Vol. 22, No. 8 (24 April, 2012): R257-R262. DOI. © 2012 Elsevier. Used with permission.

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