Including Aortic Valve Morphology in Computational Fluid Dynamics Simulations: Initial Findings and Application to Aortic Coarctation

Authors

David C. Wendell, Marquette UniversityFollow
Margaret M. Samyn, Marquette UniversityFollow
Joseph Richard Cava, Marquette University
Laura M. Ellwein, Marquette UniversityFollow
Mary M. Krolikowski, Herma Heart Center Children's Hospital of WisconsinFollow
Kimberly L. Gandy, Children's Mercy Hospitals & Clinics
Andrew N. Pelech, Herma Heart Center Children's Hospital of Wisconsin
Shawn C. Shadden, Illinois Institute of Technology
John F. LaDisa, Marquette UniversityFollow

Document Type

Article

Language

eng

Format of Original

13 p.

Publication Date

2012

Publisher

Elsevier

Source Publication

Medical Engineering & Physics

Source ISSN

1350-4533

Original Item ID

doi: 10.1016/j.medengphy.2012.07.015

Abstract

Computational fluid dynamics (CFD) simulations quantifying thoracic aortic flow patterns have not included disturbances from the aortic valve (AoV). 80% of patients with aortic coarctation (CoA) have a bicuspid aortic valve (BAV) which may cause adverse flow patterns contributing to morbidity. Our objectives were to develop a method to account for the AoV in CFD simulations, and quantify its impact on local hemodynamics. The method developed facilitates segmentation of the AoV, spatiotemporal interpolation of segments, and anatomic positioning of segments at the CFD model inlet. The AoV was included in CFD model examples of a normal (tricuspid AoV) and a post-surgical CoA patient (BAV). Velocity, turbulent kinetic energy (TKE), time-averaged wall shear stress (TAWSS), and oscillatory shear index (OSI) results were compared to equivalent simulations using a plug inlet profile. The plug inlet greatly underestimated TKE for both examples. TAWSS differences extended throughout the thoracic aorta for the CoA BAV, but were limited to the arch for the normal example. OSI differences existed mainly in the ascending aorta for both cases. The impact of AoV can now be included with CFD simulations to identify regions of deleterious hemodynamics thereby advancing simulations of the thoracic aorta one step closer to reality.

Comments

Accepted version. Medical Engineering & Physics, (2012). DOI: 10.1016/j.medengphy.2012.07.015. © 2012 Elsevier. Used with permission.

Recommended Citation

Wendell, David C.; Samyn, Margaret M.; Cava, Joseph Richard; Ellwein, Laura M.; Krolikowski, Mary M.; Gandy, Kimberly L.; Pelech, Andrew N.; Shadden, Shawn C.; and LaDisa, John F., "Including Aortic Valve Morphology in Computational Fluid Dynamics Simulations: Initial Findings and Application to Aortic Coarctation" (2012). Biomedical Engineering Faculty Research and Publications. 40.
https://epublications.marquette.edu/bioengin_fac/40