Document Type
Article
Language
eng
Publication Date
2-2017
Publisher
Oxford University Press
Source Publication
Cerebral Cortex
Source ISSN
1047-3211
Abstract
Voluntary movement initiation involves the engagement of large populations of motor cortical neurons around movement onset. Despite knowledge of the temporal dynamics that lead to movement, the spatial structure of these dynamics across the cortical surface remains unknown. In data from 4 rhesus macaques, we show that the timing of attenuation of beta frequency local field potential oscillations, a correlate of locally activated cortex, forms a spatial gradient across primary motor cortex (MI). We show that these spatio-temporal dynamics are recapitulated in the engagement order of ensembles of MI neurons. We demonstrate that these patterns are unique to movement onset and suggest that movement initiation requires a precise spatio-temporal sequential activation of neurons in MI.
Recommended Citation
Best, Matthew D.; Suminski, Aaron J.; Takahashi, Kazutaka; Brown, Kevin A.; and Hatsopoulos, Nicholas G., "Spatio-Temporal Patterning in Primary Motor Cortex at Movement Onset" (2017). Biomedical Engineering Faculty Research and Publications. 485.
https://epublications.marquette.edu/bioengin_fac/485
ADA Accessible Version
Comments
Accepted version. Cerebral Cortex, Vol. 27, No. 2 (February 1, 2017): 1491-1500. DOI. © The Author 2016. Published by Oxford University Press. Used with permission.