Evidence for Covalent Linkage Between Some Plasma α2-Antiplasmin Molecules and Aα Chains of Circulating Fibrinogen
Journal of Thrombosis and Haemostasis
Original Item ID
Plasma alpha2-antiplasmin (α2AP) is a single-chain serine protease inhibitor acting mainly through the fibrinolytic system. Its physiological importance is underscored by the observation that homozygous α2AP deficiency results in a severe hemorrhagic disorder due to rapid fibrin clot lysis (hyperfibrinolysis).
Mosesson, Michael W.; Holyst, Trudy; Hernandez, Irene; and Siebenlist, Kevin R., "Evidence for Covalent Linkage Between Some Plasma α2-Antiplasmin Molecules and Aα Chains of Circulating Fibrinogen" (2013). Biomedical Sciences Faculty Research and Publications. 218.
ADA Accessible Version
Accepted version. Journal of Thrombosis and Haemostasis, Vol. 11, No. 5 (May 2013): 995-998. DOI. © 2013 Wiley. Used with permission.