Journal of Thrombosis and Haemostasis
Original Item ID
Plasma alpha2-antiplasmin (α2AP) is a single-chain serine protease inhibitor acting mainly through the fibrinolytic system. Its physiological importance is underscored by the observation that homozygous α2AP deficiency results in a severe hemorrhagic disorder due to rapid fibrin clot lysis (hyperfibrinolysis).
Mosesson, Michael W.; Holyst, Trudy; Hernandez, Irene; and Siebenlist, Kevin R., "Evidence for Covalent Linkage Between Some Plasma α2-Antiplasmin Molecules and Aα Chains of Circulating Fibrinogen" (2013). Biomedical Sciences Faculty Research and Publications. 218.
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