Concerted and Sequential Pathways of Proton-coupled Electron Transfer in Hydrogen Halide Elimination

Authors

Aimable Kalume, Marquette UniversityFollow
Lisa George, Marquette University
Nicole Cunningham, Marquette University
Scott Reid, Marquette UniversityFollow

Document Type

Article

Publication Date

2013

Publisher

Elsevier

Source Publication

Chemical Physics Letters

Source ISSN

0009-2614

Abstract

Proton-coupled electron transfer (PCET) is a key reaction in a diverse array of chemical and biochemical processes. Concerted PCET, a single step process where no intermediates are expected, is often difficult to distinguish from sequential electron transfer/proton transfer (or proton transfer/electron transfer) events that involve one or more reactive intermediates. Here we demonstrate that in an apparently simple and fundamental organic reaction, hydrogen halide elimination (dehydrohalogenation), both mechanisms occur, with concerted PCET kinetically favored over sequential ET/PT. The latter involves a well-defined reactive intermediate, the corresponding iso-halon.

Comments

Accepted version. Chemical Physics Letters, Vol. 556 (2013): 35-38. DOI. © 2013 Elsevier. Used with permission.

Recommended Citation

Kalume, Aimable; George, Lisa; Cunningham, Nicole; and Reid, Scott, "Concerted and Sequential Pathways of Proton-coupled Electron Transfer in Hydrogen Halide Elimination" (2013). Chemistry Faculty Research and Publications. 268.
https://epublications.marquette.edu/chem_fac/268