Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection

Authors

V. Vanek, Academy of Sciences of the Czech RepublicFollow
J. Picha, Academy of Sciences of the Czech Republic
M. Budesinsky, Academy of Sciences of the Czech RepublicFollow
M. Sanda, Academy of Sciences of the Czech Republic
J. Jiracek, Academy of Sciences of the Czech RepublicFollow
Richard C. Holz, Marquette University
J. Hlavacek, Academy of Sciences of the Czech RepublicFollow

Document Type

Article

Publication Date

2010

Source Publication

Protein & Peptide Letters

Source ISSN

0929-8665

Abstract

The search for potential inhibitors that target so far unexplored bacterial enzyme mono-N-succinyl-L,Ldiaminopimelic acid desuccinylase (DapE) has stimulated a development of methodology for quick and efficient preparation of mono-N-acylated 2,6-diaminopimelic acid (DAP) derivatives bearing the different carboxyl groups or lipophilic moieties on their amino group.

Comments

Protein & Peptide Letters. Vol. 17, No. 3 (2010): 405-409. DOI.

Richard C. Holz was affiliated with Loyola University-Chicago at the time of publication.

Recommended Citation

Vanek, V.; Picha, J.; Budesinsky, M.; Sanda, M.; Jiracek, J.; Holz, Richard C.; and Hlavacek, J., "Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection" (2010). Chemistry Faculty Research and Publications. 293.
https://epublications.marquette.edu/chem_fac/293