Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection
Protein & Peptide Letters
The search for potential inhibitors that target so far unexplored bacterial enzyme mono-N-succinyl-L,Ldiaminopimelic acid desuccinylase (DapE) has stimulated a development of methodology for quick and efficient preparation of mono-N-acylated 2,6-diaminopimelic acid (DAP) derivatives bearing the different carboxyl groups or lipophilic moieties on their amino group.
Vanek, V.; Picha, J.; Budesinsky, M.; Sanda, M.; Jiracek, J.; Holz, Richard C.; and Hlavacek, J., "Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection" (2010). Chemistry Faculty Research and Publications. 293.
Protein & Peptide Letters. Vol. 17, No. 3 (2010): 405-409. DOI.
Richard C. Holz was affiliated with Loyola University-Chicago at the time of publication.