Synthetic Studies of Ambruticin: Preparation of the C1-C8 Tetrahydropyran and the C17-C24 Dihydropyran Segments

Authors

Luping Liu, Marquette UniversityFollow
Julie L. Wondergem, Marquette University
William A. Donaldson, Marquette UniversityFollow

Document Type

Article

Language

eng

Format of Original

9 p.

Publication Date

2015

Publisher

Mediterranean Journal of Chemistry

Source Publication

Mediterranean Journal of Chemistry

Source ISSN

2028-3997

Original Item ID

doi: 10.13171/mjc.4.4.2015.07.01.13.37/donaldson

Abstract

The C1-C8 tetrahydropyran and the C17-C24 dihdropyran segments of ambruticin were prepared from L-arabinose in 11 steps, 7.6% overall yield and from (S)-ethyl lactate in 8 steps, 22.2% overall yield respectively.

Comments

Published version. Mediterranean Journal of Chemistry, Vol. 4, No. 4 (2015): 176-184. DOI. © 2015 Mediterranean Journal of Chemistry. Used with permission.

Recommended Citation

Liu, Luping; Wondergem, Julie L.; and Donaldson, William A., "Synthetic Studies of Ambruticin: Preparation of the C1-C8 Tetrahydropyran and the C17-C24 Dihydropyran Segments" (2015). Chemistry Faculty Research and Publications. 444.
https://epublications.marquette.edu/chem_fac/444