Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes

Authors

Hanbin Lee, Marquette UniversityFollow
Chae S. Yi, Marquette UniversityFollow

Document Type

Article

Language

eng

Format of Original

6 p.

Publication Date

3-2015

Publisher

Wiley-VCH Verlag

Source Publication

European Journal of Organic Chemistry

Source ISSN

1434-193x

Original Item ID

DOI: 10.1002/ejoc.201403518

Abstract

The cationic ruthenium hydride complex [(C₆H₆)(PCy₃)(CO)RuH]⁺BF₄⁻ has been found to be an effective catalyst for the oxidative C–H coupling reaction of phenols with aldehydes to give 2-acylphenol compounds. The coupling of phenols with α,β-unsaturated aldehydes selectively gives the flavene derivatives. The catalytic method mediates direct oxidative C–H coupling of phenol and aldehyde substrates without using any metal oxidants or forming wasteful byproducts.

Comments

Accepted version. European Journal of Organic Chemistry, Vol 9 (March 2015): 1899-1904. DOI. © 2015 Wiley-VCH Verlag. Used with permission.

This is the pre-peer reviewed version of the following article: "Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes" European Journal of Organic Chemistry, Vol 9 (March 2015): 1899-1904., which has been published in final form at DOI.

Recommended Citation

Lee, Hanbin and Yi, Chae S., "Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes" (2015). Chemistry Faculty Research and Publications. 483.
https://epublications.marquette.edu/chem_fac/483