Carbocyclic and nitrogen-containing fused CH-acids with an annelated indenyl fragment. Thermogravimetric and X-ray structural analysis of 6H-indeno[1,2-b]quinoline
Document Type
Article
Language
eng
Publication Date
4-1995
Publisher
Springer
Source Publication
Russian Chemical Bulletin
Source ISSN
1066-5285
Abstract
Based on thermogravimetric characteristics first obtained for the model 6H-indeno [1,2-b]quinoline, the scheme of thermal conversions of this compound in the temperature range 20–700 °C has been proposed, and the limit of its thermal stability (∼300 °C) has been determined. This temperature is recommended as the optimum for synthesizing fused benzoaza(diaza)fluorenes. Based on the results of X-ray structural analysis, the molecules of the studied indenoquinoline form centrosymmetric pairs, which are arranged in (110) layers. The molecules are orientationally disordered. The observed self-association of these molecules is similar to the π-π association of fused heterocyclic systems with π-excessive and π****- deficient fragments. It has been suggested that interferon-inducing and antitumor compounds with an annelated indenyl fragment have a common mechanism of action according to the intercalation model of stacking structures.
Recommended Citation
Pleshakov, V. G.; Akimov, V. M.; Nava, E. Huipe; Lindeman, Sergey; Struchkov, Yu T.; Ambacheu, K. D.; Dudareva, A. G.; Ryashentseva, M. A.; Zvolinsky, V. P.; and Prostakov, N, S., "Carbocyclic and nitrogen-containing fused CH-acids with an annelated indenyl fragment. Thermogravimetric and X-ray structural analysis of 6H-indeno[1,2-b]quinoline" (1995). Chemistry Faculty Research and Publications. 649.
https://epublications.marquette.edu/chem_fac/649
Comments
Russian Chemical Bulletin, Vol. 44, No. 4 (April 1995): 682-688. DOI.
Sergey Lindeman was affiliated with A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russian Federation at time of publication.