Diastereoselective Alkylation of Tricarbonyl(methyl 3,5-hexadienoate)iron
Alkylation of the anion of the title compound with iodomethane, benzylbromide, or allyl bromide proceeds in a highly diastereoselective fashion to afford tricarbonyl(2S*,3R* methyl 2-substituted-3,5-hexadienoate) iron complexes. The relative stereochemistry of the methylation product 2awas determined by single X-ray crystallographic analysis of the corresponding diastereomeric carboxylic acid 4b.
Alkylation of the enolate of the title compound proceeds in a highly diastereoselective fashion to afford (2S*, 3R* methyl 2-substituted-3,5-hexadienoate)Fe(CO)3.
Donaldson, William; Craig, Richard; and Spanton, Stephen, "Diastereoselective Alkylation of Tricarbonyl(methyl 3,5-hexadienoate)iron" (1992). Chemistry Faculty Research and Publications. 846.