Alkylation of Tricarbonyl(diene)iron Complexes: Model Studies for the Preparation of Protomycinolide IV

Authors

James Thomas Wasicak, Abbott LaboratoriesFollow
Richard A. Craig, Abbott LaboratoriesFollow
Rodger Henry, Abbott Laboratories
Bireshwar Dasgupta, Marquette University
Huameng Li, Marquette University
William Donaldson, Marquette UniversityFollow

Document Type

Article

Language

eng

Publication Date

3-24-1997

Publisher

Elsevier

Source Publication

Tetrahedron

Source ISSN

0040-4020

Abstract

The alkylation of (4,6-heptadien-3-one)- and (methyl 3,5-hexadienoate)Fe(CO)₃ (1 and 2) were examined (0–42% de and 69–92% de respectively). Optically active (methyl 3,5-hexadienoate)Fe(CO)₃ (−)-2 was prepared by resolution of the corresponding carboxylic acid complex with α-methylbenzylamine.

The alkylation of (4,6-heptadien-3-one)-Fe(CO)₃ (1, 0–42% de) and (methyl 3,5-hexadienoate)Fe(CO)₃ (2, 70–92% de) were examined.

Comments

Tetrahedron, Vol. 53, No. 12 (March 24, 1997): 4185-4198. DOI.

Recommended Citation

Wasicak, James Thomas; Craig, Richard A.; Henry, Rodger; Dasgupta, Bireshwar; Li, Huameng; and Donaldson, William, "Alkylation of Tricarbonyl(diene)iron Complexes: Model Studies for the Preparation of Protomycinolide IV" (1997). Chemistry Faculty Research and Publications. 859.
https://epublications.marquette.edu/chem_fac/859