Document Type
Article
Language
eng
Publication Date
2014
Publisher
Hindawi Publishing Corporation
Source Publication
Advances in Physical Chemistry
Source ISSN
1687-7985
Abstract
Nanodimensional layered metal hydroxides such as layered double hydroxides (LDHs) and hydroxy double salts (HDSs) can undergo anion exchange reactions releasing intercalated anions. Because of this, these metal hydroxides have found applications in controlled release delivery of bioactive species such as drugs and pesticides. In this work, isomers of hydroxycinnamate were used as model compounds to systematically explore the effects of anion structure on the rate and extent of anion release in HDSs. Following intercalation and subsequent release of the isomers, it has been demonstrated that the nature and position of substituent groups on intercalated anions have profound effects on the rate and extent of release. The extent of release was correlated with the magnitude of dipole moments while the rate of reaction showed strong dependence on the extent of hydrogen bonding within the layers. The orthoisomer showed a more sustained and complete release as compared to the other isomers.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Majoni, Stephen and Hossenlopp, Jeanne M., "Controlled Release Kinetics in Hydroxy Double Salts: Effect of Host Anion Structure" (2014). Chemistry Faculty Research and Publications. 900.
https://epublications.marquette.edu/chem_fac/900
Comments
Published version. Advances in Physical Chemistry, Volume 2014, Article ID 710487 (2014): 1-12. DOI. © 2014 Stephen Majoni and Jeanne M. Hossenlopp. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.