Royal Society of Chemistry
A nonheme Fe(II) complex (1) that models substrate-bound cysteine dioxygenase (CDO) reacts with O2 at −80 °C to yield a purple intermediate (2). Analysis with spectroscopic and computational methods determined that 2 features a thiolate-ligated Fe(III) center bound to a superoxide radical, mimicking the putative structure of a key CDO intermediate.
Fischer, Anne A.; Lindeman, Sergey V.; and Fiedler, Adam T., "A Synthetic Model of the Nonheme Iron–Superoxo Intermediate of Cysteine Dioxygenase" (2018). Chemistry Faculty Research and Publications. 961.
ADA accessible version
Accepted version. Chemical Communications, Vol. 54, (2018): 11344-11347. DOI. © 2018 The Royal Society of Chemistry. Used with permission.