Document Type
Article
Language
eng
Publication Date
3-2017
Publisher
Nature Publishing Group (Macmillan Publishers Limited)
Source Publication
Journal of Antibiotics
Source ISSN
0021-8820
Abstract
Lyme disease is the most rapidly growing tick borne zoonotic disease of the Northern Hemisphere and is among the 10 most commonly reported nationally notifiable diseases in the United States.1 Clinical presentations include erythema migrans, fever, chills, muscle and joint pain.2, 3 Though these symptoms tend to fade away even without therapeutic intervention, a significant number of untreated patients develop arthritis and persistent myalgia following exposure to Borrelia burgdorferi.4 Furthermore, 10–20% of patients treated for Lyme disease develop symptoms considered typical, or even exaggerated, including muscle, joint pain and generalized fatigue5, 6. This condition is referred as post-treatment lyme disease syndrome (PTLDS).
Recommended Citation
Pothineni, Venkata Raveendra; Wagh, Dhananjay; Babar, Mustafeez Mujtaba; Inayathullah, Mohammed; Watts, R. Edward; Kim, Kwang-Min; Parekh, Mansi B.; Gurjarpadhye, Abhijit Achyut; Solow-Cordero, David; Tayebi, Lobat; and Rajadas, Jayakumar, "Screening of NCI-DTP Library to Identify New Drug Candidates for Borrelia burgdorferi" (2017). School of Dentistry Faculty Research and Publications. 190.
https://epublications.marquette.edu/dentistry_fac/190
Comments
Accepted version. Journal of Antibiotics, Vol. 70, (March 2017): 308-312. DOI. © 2017 Nature Publishing Group. Used with permission.