Magnetic Dual-Template Molecularly Imprinted Polymer Based on Syringe-To-Syringe Magnetic Solid-Phase Microextraction for Selective Enrichment Of P-Coumaric Acid and Ferulic Acid from Pomegranate, Grape, And Orange Samples

Authors

Ebrahim Alipanahpour Dil, Yasouj UniversityFollow
Mehrorang Ghaedi, Yasouj University
Arash Asfaram, Yasouj University
Fatemah Mehrabi, Yasouj UniversityFollow
Ardeshir Shokrollahi, Yasouj University
Amir Abbas Matin, Azarbaijan Shahid Madani University
Lobat Tayebi, Marquette UniversityFollow

Document Type

Article

Publication Date

9-2020

Publisher

Elsevier

Source Publication

Food Chemistry

Source ISSN

0308-8146

Abstract

Magnetic dual-template molecularly imprinted polymer (Fe₃O₄@SiO₂-MDMIP) was prepared to enrich and determine both p-Coumaric acid (p-CA) and ferulic acid (FA) based on syringe-to-syringe magnetic solid-phase microextraction (SS-MSPME). The obtained MDMIP was characterized and recognized, and then its adsorbing performance was studied. Based on the results, the Fe₃O₄@SiO₂-MDMIP indicated selective recognition towards p-CA and FA with large adsorption capacity. The optimization of MDMIP–SS-MSPME conditions (pH, Fe₃O₄@SiO₂-MDMIP mass, NaCl concentration, number of cycle, and elution volume) were conducted using the central composite design (CCD). Under the optimum conditions, an effectual and a convenient method was established to determine p-CA and FA in pomegranate, grapes, and orange samples based on SS-MSPME coupling with high-performance liquid chromatography-ultraviolet (HPLC-UV). Our developed method showed the limit of detection (LOD) of 0.08 ng mL⁻¹ for p-CA and 0.07 ng mL⁻¹ for FA. The method also indicated good linearity with R² > 0.99 and good recoveries of 85.12–94.96% with RSDs ≤ 5.58% spiked at three various concentration levels in pomegranate, grapes, and orange samples.

Comments

Accepted version. Food Chemistry, Vol. 325 (September 2020): 126902. DOI. © 2020 Elsevier. Used with permission.

Recommended Citation

Alipanahpour Dil, Ebrahim; Ghaedi, Mehrorang; Asfaram, Arash; Mehrabi, Fatemah; Shokrollahi, Ardeshir; Matin, Amir Abbas; and Tayebi, Lobat, "Magnetic Dual-Template Molecularly Imprinted Polymer Based on Syringe-To-Syringe Magnetic Solid-Phase Microextraction for Selective Enrichment Of P-Coumaric Acid and Ferulic Acid from Pomegranate, Grape, And Orange Samples" (2020). School of Dentistry Faculty Research and Publications. 435.
https://epublications.marquette.edu/dentistry_fac/435