Title

Bioresorbable Composite Polymeric Materials for Tissue Engineering Applications

Document Type

Article

Publication Date

2021

Publisher

Taylor & Francis

Source Publication

International Journal of Polymeric Materials and Polymeric Biomaterials

Source ISSN

0091-4037

Original Item ID

DOI: 10.1080/00914037.2020.1765365

Abstract

This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresobable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contain hydrolyzable bonds, which are subjected to chemical degradation via either reactive hydrolysis or enzyme-catalyzed active hydrolysis. For synthetic polymers, chemical hydrolysis is the most important mode of degradation. The degradation rate can be controlled by varying the molecular weight and crystallinity. Examples of bioresorbable polymers are: polyurethane, poly(D,L)lactide, poly(lactic-co-glycolic) acid, poly(α-hydroxy acids), cross-linked polyester hydrogels, poly(orthoesters), polyanhydrides and polyethylene glycol.

Comments

International Journal of Polymeric Materials and Polymeric Biomaterials, Vol. 70, No. 13 (2021): 926-940. DOI.

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