Electrophysiological Effects of Extracellular Electric Fields on the Individual Neuron Studied by Mathematical Modeling and Bioelectric Methods
Date of Award
Dissertation - Restricted
Doctor of Philosophy (PhD)
Electrical and Computer Engineering
Horgan, James D.
Nervous tissue is known to be responsive to extracellular currents, but externally induced alterations in the individual neuron properties are not well defined. Consequently, this work seeks to establish the specific cellular characteristics such as transmembrane polarizations which control the individual neuron's response to applied currents. This information is generally applicable to the evaluations of functional effects of extracellular current flow through nervous tissue.