Date of Award

Summer 1992

Document Type

Dissertation - Restricted

Degree Name

Doctor of Philosophy (PhD)



First Advisor

Donaldson, William

Second Advisor

Hossenlopp, Jeanne

Third Advisor

McKinney, Michael


The application of organoiron complexes in the organic synthesis has recently shown great promise due to their ease of preparation, resolution and diastereoselective reactivities. This study explores the possibility of utilizing these complexes for the synthesis of biological interesting linear polyenes--leukotrienes. The total syntheses of racemic and optically active 5-HETE methyl ester have been accomplished by the established methodologies.


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