Date of Award
2-1967
Document Type
Dissertation - Restricted
Degree Name
Doctor of Philosophy (PhD)
Department
Medical
First Advisor
Robert W. Rasch
Second Advisor
Howard M. Klitgaard
Third Advisor
Alvin F. Rieck
Abstract
The giant larval chromosomes of Diptera provide excellent material for the study of cellular control mechanisms. One of these mechanisms, control of differentiation by control of differential gene activation, has remained refractory to investigation by a variety of disciplines. This cytological study is an attempt to elucidate the synthetic patterns of the three major nuclear components during a critical stage in larval development and to relate these patterns to the phenomenon of puffing, the structural manifestation of differential gene activation
COinS