Date of Award
8-1972
Document Type
Dissertation - Restricted
Degree Name
Doctor of Philosophy (PhD)
Department
Medical
First Advisor
Robert G. Kemp
Second Advisor
Deane N. Calvert
Third Advisor
Beatrice Kassell
Fourth Advisor
Walter W. Fredricks
Fifth Advisor
Fumito Taketa
Abstract
In this dissertation, control of cAMP metabolism has been studied by two approaches. One is the purification, Characterization, and a study of the mechanism of control of cAMP phosphodiesterase from rabbit skeletal muscle. The other is the study of the properties and hormonal responsiveness of adenylate cyclase from mouse thymus.
The results of the former study have been published (Huang, Y.C., and Kemp, R.G., Biochemistry, 12, 2278 (1971).)
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