Document Type

Article

Language

eng

Publication Date

11-2011

Publisher

Elsevier

Source Publication

PM & R

Source ISSN

1934-1482

Original Item ID

DOI: 10.1016/j.pmrj.2011.02.014

Abstract

Objective

To determine if folic acid supplementation improves vascular function (brachial artery flow-mediated dilation [FMD]) in professional dancers with known endothelial dysfunction.

Design

Prospective cross-sectional study.

Setting

Academic institution in the Midwestern United States.

Subjects

Twenty-two professional ballet dancers volunteered for this study.

Main Outcome Measures

Subjects completed a 3-day food record to determine caloric and micronutrient intake. Menstrual status was determined by interview and questionnaire. Endothelial function was determined as flow-induced vasodilation measured by high-frequency ultrasound of the brachial artery. A change in brachial diameter of

Results

Sixty-four percent of dancers (n = 14) had abnormal brachial artery FMD (P< .0001).

Conclusions

This study reveals that vascular endothelial function improves in dancers after supplementation with folic acid (10 mg/day) for at least 4 weeks. This finding may have clinically important implications for future cardiovascular disease risk prevention.

Comments

Accepted version. PM & R, Vol. 3, No. 11 (November 2011): 1005-1012. DOI. © 2011 Elsevier. Used with permission.

NOTICE: this is the author’s version of a work that was accepted for publication in PM & R. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PM & R, VOL 3, ISSUE 11, November 2011, DOI.

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