Document Type

Article

Publication Date

9-2019

Publisher

Wiley

Source Publication

Journal of Hospital Medicine

Source ISSN

1553-5592

Original Item ID

DOI: 10.12788/jhm.3212

Abstract

BACKGROUND

Each hospital day of delirium incurs greater healthcare costs, higher levels of care, greater staff burden, and higher complication rates. Accordingly, administrators are incentivized to identify models of care that reduce delirium rates and associated costs.

PURPOSE

We present a systematic review and meta-analysis of delirium prevention models of care.

DATA SOURCES

Ovid MEDLINE, CINAHL, Cochrane Database of Systematic Reviews, EMBASE, and PsycINFO.

STUDY SELECTION

Eligible models of care were defined as provider-oriented interventions involving revision of professional roles, multidisciplinary teams, and service integration. Included studies implemented multidomain, multicomponent interventions, used a validated delirium instrument, and enrolled a control group to evaluate efficacy or effectiveness.

DATA EXTRACTION

We extracted data on study design; Population, model of care, outcomes, and results.

DATA SYNTHESIS

A total of 15 studies were included. All but two studies reported reduction in delirium or its duration, and 11 studies reported statistically significant improvements. Using random effects models, the pooled odds ratios of delirium incidence were 0.56 (95% CI: 0.37-0.85) from three randomized controlled trials, 0.63 (95% CI 0.37-1.07) from four pre–post intervention studies, and 0.79 (95% CI: 0.46-1.37) from three additional nonrandomized studies.

CONCLUSIONS

Several models of care can prevent delirium. In general, higher quality studies were more likely to demonstrate statistical significance of an effect. The diverse models of care included here explored interventions adapted to specific care settings, especially by addressing setting-specific delirium risk factors. These care models illustrate a range of promising strategies that deserve growing recognition, refinement, and implementation.

Comments

Accepted version. Journal of Hospital Medicine, Vol. 14, No. 9 (September 2019): 558-564. DOI. This article is © 2019 Society of Hospital Medicine. Used with permission.

Maharaj Singh was affiliated with Aurora Research Institute, Aurora Health Care, Milwaukee, WI at the time of publication.

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