Document Type
Article
Publication Date
1-30-2025
Publisher
Elsevier
Source Publication
Women's Health Issues
Source ISSN
1049-3867
Original Item ID
DOI: 10.1089/whr.2024.0157
Abstract
Background: Measuring quantitative menstrual cycle hormones at home may help women better understand their postpartum and perimenopause fertility transitions, but these quantitative fertility monitors require validation.
Materials and Methods: This study included 16 North American women, aged 28–51, during either the postpartum (n = 8, cycles = 18) or perimenopause (n = 8, cycles = 35) fertility transitions testing daily firstmorning urine testing with both the Mira Monitor and ClearBlue Fertility Monitor (CBFM) along with menstrual cycle parameter tracking. The main outcome measures were a rise in estrone-3-glucuronide (E13G) and luteinizing hormone (LH) urine hormone values from the Mira monitor correlated to low, high, or peak values on the CBFM.
Results: Both in the postpartum and perimenopause transitions, the identification of the day of ovulation based on the LH surge on the Mira and CBFM monitors was highly correlated (R = 0.94 and 0.83, p < 0.001). The E13G levels on the Mira monitor were significantly higher for a CBFM reading of “High” compared with “Low” for both the postpartum and perimenopausal cycles (all p < 0.001). Similarly, the LH levels on the Mira monitor were significantly higher for a CBFM reading of “Peak” (LH surge) compared with “High” for both the postpartum and perimenopausal cycles (all p < 0.001).
Conclusions: The LH surge and levels of E13G in urine identified on the quantitative Mira fertility monitor strongly correlate to the LH surge and the shift from low to high on the CBFM during the postpartum and perimenopause transitions.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Bouchard, Thomas; Doyle-Baker, Patricia K.; Yong, Paul J.; Fehring, Richard; and Schneider, Mary, "Validating At-Home Urinary Hormone Measurements in Postpartum and Perimenopause Fertility Transitions" (2025). College of Nursing Faculty Research and Publications. 1318.
https://epublications.marquette.edu/nursing_fac/1318
Comments
Published version. Women’s Health Reports, Vol. 6, No. 1 (2025): 369-376. DOI. This article is © The Authors, published by Mary Ann Liebert, Inc. Used with permission.
This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.