Severity of Post-traumatic Stress and Non-medical, Concomitant Opioid and Benzodiazepine Use in a Sample of Women at High Risk of Overdose

Document Type

Article

Publication Date

2023

Publisher

Springer

Source Publication

International Journal of Mental Health and Addiction

Source ISSN

1557-1874

Original Item ID

DOI: 10.1007/s11469-023-01169-w

Abstract

Women who exchange sex and use opioids experience substantial post-traumatic stress disorder (PTSD) symptoms. Among veterans, PTSD increases the risk of concomitant opioid-benzodiazepine use, increasing overdose risk, but this relationship is underexplored in other at-risk populations. We examined correlates of non-medical benzodiazepine use among a cohort of women who exchange sex and use opioids daily (N = 270) in Baltimore, MD. PTSD symptom severity was measured by the full PCL-5 (possible range: 0–80, categorized by tertile as low, medium, high) and four symptom-specific subscales. The prevalence of benzodiazepine use was 27% and the median PCL-5 score was 34. In adjusted models, women with high PCL-5 scores were more likely to use benzodiazepines than those with low scores, overall and across subscales. Severe PTSD symptoms conferred elevated risk of concomitant opioid-benzodiazepine use, calling attention to the importance of addressing trauma in combating the opioid and overdose crises.

Comments

International Journal of Mental Health and Addiction, 2023. DOI. Online before print.

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