Rebuttal: Reduced Oxidative Capacity of Skeletal Muscle Is NOT an Inevitable Consequence of Adult Ageing

Authors

Ian R. Lanza, Mayo Clinic
Christopher W. Sundberg, Marquette UniversityFollow
Jane A. Kent, University of Massachusetts Amherst

Document Type

Article

Publication Date

1-2025

Publisher

Wiley

Source Publication

Journal of Physiology

Source ISSN

0022-3751

Original Item ID

DOI: 10.1113/JP286695

Abstract

We thank Drs Marcinek and Ferrucci for their perspective on the inevitability of age-related declines in skeletal muscle oxidative capacity (Marcinek & Ferrucci, 2025). We agree that mitochondria have numerous roles in the cell beyond provision of chemical energy, many of which may be altered by ageing, but our focus in this debate is entirely on its role in energy production.

Comments

Accepted version. Journal of Physiology, Vol. 603, No. 1 (2025): 27-28. DOI. © 2025 Wiley. Used with permission.

Recommended Citation

Lanza, Ian R.; Sundberg, Christopher W.; and Kent, Jane A., "Rebuttal: Reduced Oxidative Capacity of Skeletal Muscle Is NOT an Inevitable Consequence of Adult Ageing" (2025). Physical Therapy Faculty Research and Publications. 239.
https://epublications.marquette.edu/phys_therapy_fac/239