Document Type
Article
Language
eng
Publication Date
2-2009
Publisher
Cambridge University Press
Source Publication
Journal of the International Neuropsychological Society
Source ISSN
1355-6177
Original Item ID
DOI: 10.1017/S1355617708090103
Abstract
Person identification represents a unique category of semantic knowledge that is commonly impaired in Alzheimer's disease (AD), but has received relatively little investigation in patients with mild cognitive impairment (MCI). The current study examined the retrieval of semantic knowledge for famous names from three time epochs (recent, remote, and enduring) in two participant groups: 23 amnestic MCI (aMCI) patients and 23 healthy elderly controls. The aMCI group was less accurate and produced less semantic knowledge than controls for famous names. Names from the enduring period were recognized faster than both recent and remote names in both groups, and remote names were recognized more quickly than recent names. Episodic memory performance was correlated with greater semantic knowledge particularly for recent names. We suggest that the anterograde memory deficits in the aMCI group interferes with learning of recent famous names and as a result produces difficulties with updating and integrating new semantic information with previously stored information. The implications of these findings for characterizing semantic memory deficits in MCI are discussed. (JINS, 2009, 15, 9-18.)
Recommended Citation
Seidenberg, Michael; Guidotti, Leslie; Nielson, Kristy A.; Woodard, John L.; Durgerian, Sally; Zhang, Qi; Gander, Amelia; Antuono, Piero; and Rao, Stephen M., "Semantic Knowledge for Famous Names in Mild Cognitive Impairment" (2009). Psychology Faculty Research and Publications. 100.
https://epublications.marquette.edu/psych_fac/100
Comments
Published version. Journal of the International Neuropsychological Society, Vol. 15, No. 1 (January 2009): 9-18. DOI. © 2009 Cambridge University Press. Used with permission.