Document Type

Article

Publication Date

2025

Publisher

Frontiers Media S.A.

Source Publication

Frontiers in Aging Neuroscience

Source ISSN

1663-4365

Original Item ID

DOI: 10.3389/fnagi.2025.1568173

Abstract

Anosognosia, or the lack of awareness of cognitive, behavioral, or functional deficits, represents a critical challenge in the clinical management of neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal dementia. This condition not only impacts patients, caregivers, and healthcare systems (D'Souza et al., 2011; Turró-Garriga et al., 2013) but also raises important questions about its underlying mechanisms and evolution (Hanseeuw et al., 2020; Starkstein, 2014; Vannini et al., 2017). Despite its critical importance, significant gaps remain in our understanding of cognitive self-awareness in neurodegenerative diseases. Building on the momentum of the first edition of To Know or Not to Know, this second volume continues to explore these pressing issues through innovative approaches and multidisciplinary perspectives. The eight articles in this volume span a diverse range of themes and methodologies, reflecting the multifaceted nature and importance of awareness research.

Comments

Published version. Frontiers in Aging Neuroscience, Vol. 17 (2025). DOI. © 2025 Cacciamani, Nielson, Hanseeuw, Gagliardi and Vannini. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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