Date of Award
Spring 1999
Document Type
Thesis - Restricted
Degree Name
Master of Science (MS)
Department
Chemistry
First Advisor
Tran, Chieu D.
Second Advisor
Haworth, Daniel T.
Third Advisor
Hoffman, Norman E.
Abstract
Chiral separation remains one of the most challenging tasks in analytical chemistry. Enantiomers of chiral drugs often exhibit different pharmacological and toxicological properties, and this knowledge prompts the demand for a fast, reliable separation approach. In the past, high performance liquid chromatography (HPLC) and gas chromatography (GC) were widely used for chiral separations. Capillary electrophoresis (CE) has been increasingly used since the 1980's and seems to be a promising alternative separation technique due to the advantages of high efficiency and short analysis time. However the number of available chiral selectors is limited. The objective of this thesis is to explore new surfactants and cyclooligosaccharides as chiral selectors for CE chiral separation. At the same time, the results will provide insight into the mechanism of CE chrial [sic] separation which to date is not completely understood.
Recommended Citation
Kang, Jianxia, "Development of Novel Chiral Selectors for Capillary Electrophoresis" (1999). Master's Theses (1922-2009) Access restricted to Marquette Campus. 2533.
https://epublications.marquette.edu/theses/2533