Date of Award

Spring 2002

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)

Department

Biomedical Engineering

First Advisor

Foth, Jeffrey

Second Advisor

Harris, Gerald

Third Advisor

Wang, Mei

Abstract

This project will hopefully enhance the knowledge base of the spine research community by reaching three goals. The goals of this project follow. The first goal is to evaluate the osteocompatibility of a novel titanium mesh device (Pyramesh ™). Secondly, to evaluate the efficacy of a new spinal fusion device in a sheep lumbar (L4/L5) interbody spine fusion model using blinded radiographic, biomechanic, and histologic methods. Finally, to evaluate the effects of adding rhBMP-2 on a collagen sponge and ceramic carrier in conjunction with the titanium mesh device to stimulate bony healing and fusion between vertebral bodies.

Share

COinS

Restricted Access Item

Having trouble?