Date of Award

Fall 1994

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)

Department

Biomedical Engineering

First Advisor

Ishii, Thomas K.

Second Advisor

Jeutter, Dean C.

Third Advisor

Seitz, Martin A.

Abstract

Ventricular arrythmias are among the leading causes of morbidity and mortality in the United states. Presently these arrythmias are managed by implantable pacemakers, defibrillators, and medication, however these methods are palliative and do not offer a cure. Present radio frequency catheters are unable to create lesions to ablate deep seated arrythrnogenic tissue associated with ventricular arrythmias. Surgical procedures to cure these arrythmias are both expensive and traumatic. Computer simulations have shown that microwave energy can penetrate deeper and create larger lesions than RF energy. Microwave ablation technique holds the promise of a less traumatic and economical cure for ventricular tachycardias. To produce a large lesion in endocardial tissue, various types of microwave applicators were designed and fabricated in this thesis research. Both In-vitro and In-vivo test were carried out on these applicators. Most applicators designed have been able to produce larger lesions than have been reported by other authors.

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