Date of Award
1974
Document Type
Thesis - Restricted
Degree Name
Master of Science (MS)
Department
Biomedical Engineering
First Advisor
Sances, Anthony
Second Advisor
Richardson, Bobbie
Third Advisor
Smith, James
Abstract
The accurate and precise measurement of ph, or hydrogen ion activity, in biological systems in quite complex. Chemical indicators are not usually satisfactory due to inadequate sensitivity, difficulty of detection, or interaction with the biological materials. Electrometric systems of several types are widely used, but cross comparisons are difficult and fixation of a valid reference state is perplexing. Protein interaction with electrode response, errors due to other anions and cations, the effects of colloids and suspensions, and variation of liquid junction potentials of reference electrodes are some of the sources of variability encountered in biological systems. This manuscript examines the suitability of the iridium oxide ph electrode for use in biological fluids and compares its performance with various other methods.
Recommended Citation
Houge, James C., "The Design of a Microminiature Iridium Oxide pH Electrode and Its in Vitro Characterization in Biological Media" (1974). Master's Theses (1922-2009) Access restricted to Marquette Campus. 4843.
https://epublications.marquette.edu/theses/4843