Date of Award
Spring 1978
Document Type
Thesis - Restricted
Degree Name
Master of Science (MS)
Department
Biomedical Engineering
First Advisor
llaurado, Josep G.
Second Advisor
Smith, George A.
Third Advisor
Jodat, Ronald W.
Abstract
Enzymatic reactions, diffusion phenomena, flows across membranes, and transport of materials are constantly occurring in biological systems. Of particular interest to this study were not only data on chemical composition but also quantitative characterization of the kinetics involved in the processes underlying the steady state transport and distribution of substances within living tissue. The study of sodium kinetics is particularly suited to formulating relatively simple models which make possible an interpretation of the time dependent nature of various important phenomena in different biological tissues; for example, this thesis deals with sodium movement and distribution between cells and their surrounding fluids in induced granuloma tissue. The purpose of sodium kinetics has been, and is in fact, both the study of the time variations of electrolyte concentrations in different tissues and the construction of models suited to interpret such phenomena. Since connective tissue plays such a major role in the life process, this thesis will attempt to study sodium transport and distribution in induced inflammatory tissue under in vitro conditions so that a mathematical model of the actual dynamic system of granulomous tissue can begin to be formulated. From this, it may be delineated whether Na is distributed in soluble and/or bound forms in both the extracellular and intracellular spaces...
Recommended Citation
Luetzow, Brent A., "Compartmental Analysis of Na Kinetics in Experimentally Induced Connective Tissue: Studies with Cortisol and Aldosterone" (1978). Master's Theses (1922-2009) Access restricted to Marquette Campus. 5031.
https://epublications.marquette.edu/theses/5031