Date of Award

Spring 1978

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)

Department

Dentistry

First Advisor

Meyer, Ralph A.

Second Advisor

Bell, William A.

Third Advisor

Winders, Robert V.

Abstract

By applying force to induce orthodontic tooth movement, areas of pressure and tension are created in the attachment apparatus. In areas of pressure, bone resorption, in association with the appearance of osteoclasts, is stimulated. In areas of tension, osteoblasts arise and form osteoid which is subsequently calcified. Teeth that have been moved in or through bone by such mechanical means often have a tendency to relapse to their former position. This relapse can be a significant clinical problem. Calcitonin, a polypeptide hormone, has a suppressive action on osteoclastic bone resorption. Therefore, theoretically, it may be useful in inhibiting tooth movement. This study will attempt to determine whether calcitonin does have an effect on the rate of tooth movement both under orthodontic force and during relapse.

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