Date of Award
5-1973
Document Type
Thesis - Restricted
Degree Name
Master of Science (MS)
Department
Biological Sciences
First Advisor
Howard M. Klitgaard
Second Advisor
Alvin F. Rieck
Third Advisor
William J. Stekiel
Fourth Advisor
David W. Glenister
Abstract
Thyroid hormones have a profound influence on growth and development in the mammal and metamorphosis in the amphibian. There is evidence that they also exert modifying influences on the liver during regeneration. Attempts have been made through the years to correlate these growth changes with the metabolic effects of the thyroid hormones and analogs. One variant in particular, triiodothyroacetic acid (T3AC), possesses potent metamorphic effects but only a fraction of the mammalian metabolic stimulation of triiodothyronine (T3). This study was undertaken to investigate the influence of T3 and T3AC on regenerating liver in the immature rat and to correlate the growth effects with metabolic changes that take place; namely, liver oxygen consumption, liver succinic dehydrogenase activity and whole animal basal metabolic rates.
Recommended Citation
Gaspard, Therese, "Liver Regeneration in Triiodothyronine and Triiodothyroacetic Acid Treated Immature Rats" (1973). Master's Theses (1922-2009) Access restricted to Marquette Campus. 5611.
https://epublications.marquette.edu/theses/5611