Date of Award
7-1949
Document Type
Thesis - Restricted
Degree Name
Master of Science (MS)
Department
Medical
First Advisor
Joseph F. Kuzma
Abstract
In the past, much has been written of the pathology and pathogenesis of acute myocardial infarction, and more recently of the use of the anticoagulants in the treatment of such fearful events. This is to be expected. Today cardiovascular diseases cause the greatest number of deaths in the United States, and in this group, acute myocardial infarction assumes a major role. This is undoubtedly the reason for the great amount of work already done upon this subject.
Many investigators have studied and written about the pathogenesis of atherosclerosis which is the underlying pathology of most coronary occlusions; many have puzzled over the causes of the sudden occlusive phenomenon of an already sclerotic vessel; many statistical reports in the therapeutic use of heparin and dicumarol have been published; and a smaller number of papers have appeared reporting the use of Vitamin X in the therapy of myocardial infarction. Only one case report has been seen which correlates to pathological findings with the clinical records, and especially, with the prothrombin time. This has been the aim and goal of this work. Although no startling or profound achievements were to be anticipated, it was hoped that perhaps a little more light could be shed upon a problem which is still in great need of such in its pathogenesis and therapy.
Recommended Citation
Manson, Almon A., "Hypoprothrombinemia in the Pathogenesis of Myocardial Infarction" (1949). Master's Theses (1922-2009) Access restricted to Marquette Campus. 5734.
https://epublications.marquette.edu/theses/5734