Date of Award

1966

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)

Department

Medical

First Advisor

Edwin H. Hllison

Second Advisor

Thomas Wall

Third Advisor

Joseph Kuzma

Fourth Advisor

Konrad Soergel

Abstract

In 1877 Lautenbach indicated, erroneously as it transpired, that hepatic failure was inevitable in dogs after portal vein occlusion. Eck, however, very quickly demonstrated that the portal vein in dogs could be ligated with impunity if an anastomosis was created between the splanchnic end of the occluded portal vein and the inferior vena cava, thereby shunting the portal blood directly into the systemic circulation. A quarter century elapsed before Tansin introduced the experimental equivalent of the modern end to side portocaval shunt by dividing the portal vein obliquely and suturing the splanchnic end of this vessel into the anterior wall of the vena cava. A further decade elapsed before Franke devised the experimental side to side portocaval shunt without ligation of the portal vein.

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