The Biology Dissertations Series is comprised of dissertations and theses authored by Marquette University's Biology Department doctoral and master's students.

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Theses/Dissertations from 2024

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EAAT4-Dependent Effects on Glutamatergic Signaling in the Cerebellar Molecular Layer, Christopher Chen

Theses/Dissertations from 2023

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Evidence that the Inner Nuclear Membrane is a Functional β1-Adrenergic Receptor Signaling Platform in Astrocytes, Kelsey Benton

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Altered Motivation & Dopamine Subcircuit Plasticity Unique to Sex During Protracted Opioid Withdrawal, Devan Marc Gomez

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Postnatal Developmental Trends in Membrane Excitability and BK Channel Function in the Rodent Hippocampus, Michael S. Hunsberger

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Breathing Around the Clock: Novel Circadian and Light-Driven Mechanisms That Govern Daily Breathing Behavior in Mice, Aaron Andrew Jones

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Characterizing Allosteric Regulation and Conformational Dynamics in Staphylococcus Aureus Pyruvate Carboxylase, Amanda Joan Laseke

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PROBIOTIC COMPOUNDS INHIBIT STAPHYLOCOCCUS AUREUS BIOFILM FORMATION, REDUCE VIRULENCE, & IMPROVE ANTIBIOTIC SENSITIVITY, Kyle R. Leistikow

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Improving Cold Tolerance of Asian Rice through Plant Growth Promoting Bacteria and Rice Gene Manipulation: Mechanisms of Pseudomonas Mosselli and OsMADS27, Nasim Maghboli Balasjin

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A Trait-Based Approach to Explain Plant Coexistence in Tropical Forests, Felipe Nery Arantes Mello

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Targeted Mapping of Oryza sativa Chilling Tolerance Candidate Genes Using Multiple Stress-Relevant Quantitative Traits, Naoki Simon Shimoyama

Theses/Dissertations from 2022

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Modulation of Mitochondrial Protein Synthesis in Yeast – Role of the Mrp7 (bL27) Protein, Jessica Anderson

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Embryology of the Gekkota: Insights into the Evolution an Development of Morphological Diversity, Aaron Harp Griffing

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The Ventral Hippocampus Dynamically Regulates Amygdala Encoding and Learned Fear, Matthew Richard Herbst

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Somatostatin Regulates Circadian Clock Function and Photic Processing, Deborah A. M. Joye

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Evolution of Sex Chromosomes in Geckos (Reptilia: Gekkota), Shannon Elizabeth Keating

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Explore the Regulatory Roles of Micrornas in Sperm Formation and Function of C. Elegans, Lu Lu

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Pituitary Adenylate Cylase-Activating Polypeptide Receptor: Multiple Signaling Pathways Involved in Energy Homeostasis, Brian Maunze

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Frontal-Cerebellar EEG as an Index of Risk for Alzheimer's Disease in Healthy Elders, Elizabeth Paitel

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Investigations into the Negative Impact of Temperature Stress on Fertility in Wild Strains of Caenorhabditis Elegans, Nicholas B. Sepulveda

Theses/Dissertations from 2021

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Combined Gene Therapy and Rehabilitative Approaches to Repair the Corticospinal Tract Following Injury, Audra Kramer

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Arginine Vasopressin Modulates Circadian Timekeeping in a Sex-Dependent Manner, Kayla Rohr

Theses/Dissertations from 2020

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Anthropogenic Drivers and Ecological Concepts of Antimicrobial Resistance, Rachelle E. Beattie

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Characterizing the Mechanisms of Ectopic Expression of Dream Complex Target Genes and the HTA Phenotype in C. Elegans, Jerrin Roy Cherian

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Investigating the Role of LIN-35 and the DREAM Complex in Preserving Fertility Under Stress in C. elegans, Frances Virginia Compere

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Mechanisms of ATP-Dependent Substrate Reduction in the Nitrogenase-Like DPOR Complex, Elliot Irwin Corless

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The Role of System XC- in Cognition: The Importance of Neuron-Astrocyte Signaling, Evan Michael Hess

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The Role of the Prefrontal Cortex in Aversive Memory Formation: Contribution of Sex and Circuit, Adam Kirry

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Characterization of De Novo Protein Aggregate Formation in S. Cerevisiae, Douglas Lyke

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Characterization of the MIR-44 Family of Micrornas in the C. Elegans Germline, Katherine Ann Maniates

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Small Geckos Yield Great Insight into the Patterns and Processes of Speciation and Sex Chromosome Evolution, Brendan John Pinto

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Establishing the Roles of the DNA Binding Domains of Replication Protein A (RPA), Nilisha Pokhrel

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Chronic Variable Stress Induces Avolition and Disrupts Corticoaccumbens Encoding of Approach Cues, Mitchell Spring

Theses/Dissertations from 2019

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SynMuv B Proteins Regulate Chromatin Compaction during Development, Meghan Elizabeth Costello

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Sex, Drugs, & Prefrontal Cortex: Influence of Biological Sex on Cocaine Seeking, Elizabeth M. Doncheck

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Ecological Succession in Tropical Forests: The Role of Edaphic Factors, Initial Conditions and Competition, Sergio Estrada Villegas

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Investigation of the Mechanisms Governing Carrier Domain Translocation in S. Aureus Pyruvate Carboxylase, Joshua Hakala

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The Glycosyltransferase Gene ELT1 (OsUGT90A1) Protects Plasma Membranes During Chilling Stress in Rice, Yao Shi

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Optimizing Tools for the Investigation of Flagella Protein Trafficking in Chlamydomonas Reinhardtii, Brandon M. Wills

Theses/Dissertations from 2018

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Pituitary Adenylate Cyclase-Activation Polypeptide (PACAP) Regulates Feeding in the Rat Striatum and Hypothalamus, Matthew M. Hurley

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Allosteric Regulation of Pyruvate Carboxylase, Yumeng Liu

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Importance of S. Cerevisiae Rcf1 and Rcf2 Proteins for the Mitochondrial Protonmotive Force Generation, Vera Strogolova

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Electrical and Biomechanical Properties of Rat Ventricular Myocytes: Effect of Exercise-Training & Beta-Adrenergic Regulation, Xinrui Wang

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The Discovery and Characterization of Small Molecule Inhibitors of Pyruvate Carboxylase, Brittney Wyatt

Theses/Dissertations from 2017

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CRISPR-Based Knockout Screening in Primary Neurons, Ben Callif

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Regulation of System Xc-by the Neuropeptide PACAP: Implications for Glutamate Transmission in Drug Addiction, Linghai Kong

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Rediscovery of the Microtubule System in Chlamydomonas, Yi Liu

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Functional Analysis of Microrna Pathway Genes in the Somatic Gonad and Germ Cells During Ovulation in C. Elegans, Carmela Rios

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Reductions in Mesolimbic Dopamine Signaling and Aversion: Implications for Relapse and Learned Avoidance, Mykel A. Robble

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The Noncanonical Roles of Two Primordial Molecules in Flagella, Xiaoyan Zhu

Theses/Dissertations from 2016

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Regulation of the Cystine/Glutamate Antiporter and its Contribution to Neuronal Death, Rebecca Albano

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Characterization of the RCF1 Q-X3-R-X-R-X3-Q Motif and Its Role in Supporting Oxidative Phosphorylation Enzyme Complexes, Joshua Garlich

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Examining Mechanism of Toxicity of Copper Oxide Nanoparticles to Saccharomyces Cerevisiae and Caenorhabditis Elegans, Michael Joseph Mashock

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Depletion of the RNA Helicase SKIV2L2 Impedes Mitotic Progression and Histone mRNA Turnover in Murine Cell Lines, Alexis Marie Onderak

Theses/Dissertations from 2015

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Genetic and Molecular Analysis of dec-11 in C. elegans' Intestinal Pacemaker Activity, Adele Joan Gordon

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The Role and Regulation of Quinol Oxidase in Rhizobium Etli, Zachary Ryan Lunak

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The Contribution of Syntrophic Fatty-Acid Degrading Microbial Communities to Anaerobic Digester Function and Stability, Prince Peter Mathai

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A Neurobiological Pathway That Mediates Stress-Induced Drug Use, Oliver Vranjkovic

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Targets Identification and Characterization of Tramp Comples in Mouse, Fengchao Wang

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Molecular Sites and Mechanisms of Action of Alcohol on the NMDA Receptor GluN2B Subunit, Yulin Zhao

Theses/Dissertations from 2014

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Ventral Tegmental Area Regulation Of Stress-Induced Reinstatement Of Cocaine-Seeking Behavior, Jordan Michael Blacktop

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Mechanism Of Gabab Receptor-Activated Increases In L-Type Calcium Current In The Neonatal Mammalian Hippocampus, Andrew S. Karls

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Structural and Biochemical Studies of the Carboxyltransferase Domain from Pyruvate Carboxylase, Adam David Lietzan

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Structural and Functional Studies of Urea Amidolyase, Yi Lin

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Coordination of Primer Sugar Synthesis with O-antigen Initiation in Rhizobium Etli CE3, Tiezheng Li

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Cross-Bridge Mechanisms of Skeletal Muscle Fatigue: Effects of Hydrogen Ion, Inorganic Phosphate, and Age, Cassandra Rae Nelson

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Hypothalamic Pituitary Adenylate Cyclase-Activating Polypeptide: Impact On Energy Homeostasis And Glutamate Signaling, Jon Resch

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The Role of PRKA-Mediated Stimulation of Fatty Acid Oxidation in the Regulation of Meiotic Maturation in Mouse Oocytes, Deepa Valsangkar

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Positions in the GluN2C-Containing NMDAR Regulate Alcohol Sensitivity and Ion Channel Gating, Man Wu

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Impact of Mtr4 Structural Domains on its Enzymatic Activities, in the Regulation of Nuclear RNA Turnover, Li Yan

Theses/Dissertations from 2013

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CONTRIBUTIONS OF INDIVIDUAL DIFFERENCES IN STRESS REACTIVITIY TO POST-TRAUMATIC STRESS DISORDER VULNERABILITY AND RESILIENCE, Jonathan Edward Hill

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Temporal And Spatial Requirements Of Drop-Dead Expression For Adult Survival In Drosophila Melanogaster, Christine Lynn Sansone

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The Role Of Amp-Activated Protein Kinase In Mouse Oocyte Maturation And Subsequent Egg Activation, Ru Ya

Theses/Dissertations from 2012

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Genetic Identification of Development Pathways Regulated by Conserved microRNAs in Caenorhabditis elegans, John L. Brenner

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Quantitative Analysis of Methangenic Community in Anaerobic Digesters and its Response to Freeze Drying and Exposure to Oxygen, Keerthi Cherukuri

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Corticosterone-Induced Potentiation of Cocaine Seeking: A Potential Role for Organic Cation Transporter 3, Evan N. Graf

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Myosin Isoforms and Regulation of Tonic and Phasic Contraction in Smooth Muscle, Qian Huang

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Regulation of System XC- and its Contribution to Cell Death, XiaoQian Liu

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The Contribution of System Xc-to Prefrontal Cortical Mediated Behaviors Associated with Schizophrenia, Victoria Lutgen

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Dysregulation of System Xc- and Its Impact on Cocaine Seeking, Aric Madayag

Theses/Dissertations from 2011

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The Pleiotropic Effects of LC8 on the Anchoring Protein in Flagellar Radial Spoke Complex, Anjali Gupta

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The Mitospecific Region of Mrp20 and its Importance for the Assembly of Mitochondrial Ribosomes in Saccharomyces cerevisiae, Jasvinder Kaur

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Exploring the Architecture of the Human GABA(A) Receptor Ligand Binding Pocket via Mutational, Electrophysiological, and Kinetic Analysis, Kurt Thomas Laha

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Relating Methanogen Community Structure to Function in Anaerobic Wastewater Digesters, Rachel Morris

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Mechanisms of Neuronal Death Induced by Environmental Toxicants in Murine Cortical Culture, Travis Rush

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The discovery and exploration of a universal targeting mechanism in eukaryotic cells, Priyanka Sivadas

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Mutational-kinetic Analysis Reveals the Roles of Arginines and Aromatics in the Core of the GABAA Receptor Ligand-binding Pocket, Phu Tran

Theses/Dissertations from 2010

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Modulation of L-type Calcium Current by GABA-B Receptor Activation in the Neonatal Rat Hippocampus, Jennifer Grace Bray

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Role of DPY-30 Proteins in Flagella, Radhika Gopal

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MIR-237 is Likely a Developmental Timing Gene that Regulates the L2-to-L3 Transition in C. Elegans, Xi Li

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Reversible Deficiencies in Flagellar Beating and Axonemal Assembly, Mei Wei

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Characterization of Regulatory Mechanisms for Alternative Splicing in Alpha Thyroid Hormone Receptor mRNA, Chao Zhang

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PKCα and CPI-17 expression and spatial-temporal distribution with activation in pig stomach antrum and fundus, Yu Zhang

Theses/Dissertations from 2009

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Maize Conzi Has Distinct Patterns of Expression in Different Photoperiods and Confers Photoperiod Sensitivity in Rice, Theresa A. Dlugi

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DNA Replication in the Macronuclear Anlagen of Tetrahymena Thermophila : a Model of the Endocycle, Susan T. Gater

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Mutational Analysis of the Yeast Oxa1 Protein, Sherréa A. Herod

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Biosynthesis of the Rhizobium etli CE3 O Antigen, Kristylea J. Ojeda

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Effects of Gap Junction Inhibitors on the Lamprey Locomotor Network, Peter G. Placas

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Characterizing the Functions of Arabidopsis EARLI1 Type Hybrid Proline-Rich Proteins in the Yeast Saccharomyces Cerevisiae, Ranjuna Weerasekera

Conserved Cysteines in the Vitelline Membrane Domain of the Drosophila sV23 Eggshell Protein are Functionally Distinct, Tianyi Wu

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Conserved Cysteines in the Vitelline Membrane Domain of the Drosophila sV23 Eggshell Protein are Functionally Distinct, Tianyi Wu