Synthesis and X-ray structural Investigation of 6-Chloro-10-Phenyl-1,2,3,4-Tetrahydroacridine
Russian Chemical Bulletin
An X-ray structural study of 6-chloro-10-phenyl-1,2,3,4-tetrahydroacridine prepared by the reaction of cyclohexanone with 2-amino-5-chlorobenzofenone was carried out. At 20°Ca=24.215(6),b=8.967(2),c=15.006(3) Å, β=115.57(2)°,V= 2939(1) Å3,dcalc=1.310 g cm−3,Z=4, space groupC2/c, 1324 reflections, λMoKα,R=0.038. The cyclohexene ring has a half-chair conformation. The phenyl substituent is rotated 71.2° with respect to the plane of the quinoline fragment.