Document Type

Article

Language

eng

Publication Date

11-2016

Publisher

Elsevier

Source Publication

Chemosphere

Source ISSN

0045-6535

Original Item ID

DOI: 10.1016/j.chemosphere.2016.07.097

Abstract

Bench-scale anaerobic digesters were amended to elevated steady-state concentrations of triclosan (850 mg/kg) and triclocarban (150 mg/kg) using a synthetic feed. After more than 9 solids retention time (SRT) values of acclimatization, biomass from each digester (and a control digester that received no antimicrobials) was used to assess the toxicity of three antibiotics. Methane production rate was measured as a surrogate for activity in microcosms that received doses of antibiotics ranging from no-antibiotic to inhibitory concentrations. Biomass amended with triclocarban was more sensitive to tetracycline compared to the control indicating synergistic inhibitory effects between this antibiotic and triclocarban. In contrast, biomass amended with triclosan was able to tolerate statistically higher levels of ciprofloxacin indicating that triclosan can induce functional resistance to ciprofloxacin in an anaerobic digester community.

Comments

Accepted version. Chemosphere, Vol. 163 (November 2016): 22-26. DOI. © 2016 Elsevier Ltd. Used with permission.

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