The Biomedical Sciences Faculty Research and Publications Series is comprised of books and articles published by Marquette University's biomedical sciences faculty.
Submissions from 2022
Pituitary Adenylate Cyclase-Activating Polypeptide Receptor Activation in the Hypothalamus Recruits Unique Signaling Pathways Involved in Energy Homeostasis, Brian Maunze, Katherine Wood Bruckner, Nikhil Nilesh Desai, Christopher Chen, Fanghong Chen, David Baker, and Sujean Choi
Complexes of Ghrelin GHS-R1a, GHS-R1b, and Dopamine D1 Receptors Localized in the Ventral Tegmental Area as Main Mediators of the Dopaminergic Effects of Ghrelin, Gemma Navarro, William Rea, César Quiroz, Estefanía Moreno, Devan Gomez, Cody J. Wenthur, Vicent Casadó, Lorenzo Leggio, Matthew C. Hearing, and Sergi Ferré
Craniofacial Fluctuating Asymmetry in Gorillas, Chimpanzees, and Macaques, Ashly N. Romero, D. Rex Mitchell, Siobhán B. Cooke, Claire A. Kirchhoff, and Claire E. Terhune
Submissions from 2021
Organic Cation Transporters and Nongenomic Glucocorticoid Action, Kelsey C. Benton, Christopher A. Lowry, and Paul J. Gasser
Widening Spinal Injury Research to Consider All Supraspinal Cell Types: Why We must and How We Can, Murray G. Blackmore, Eliazbeth Batsel, and Pantelis Tsoulfas
Collection of Mouse Brain Slices for Bioluminescence Imaging of Circadian Clock Networks, Jennifer A. Evans, David K. Welsh, and Alec J. Davidson
Organic Cation Transporters in Brain Catecholamine Homeostasis, Paul J. Gasser
Modulatory Actions of the Glycine Receptor β Subunit on the Positive Allosteric Modulation of Ethanol in α2 Containing Receptors, Braulio Muñoz, Trinidad Mariqueo, Pablo Murath, Christian Peters, Gonzalo E. Yevenes, Gustavo Moraga-Cid, Robert W. Peoples, and Luis G. Aguayo
Vasopressin Regulates Daily Rhythms and Circadian Clock Circuits in a Manner Influenced by Sex, Kayla Rohr, Adam Telega, Alexandra Savaglio, and Jennifer A. Evans
Chronic Stress Prevents Cortico-Accumbens Cue Encoding and Alters Conditioned Approach, Mitchell Spring, Aaron Caccamise, Elizabeth A. Panther, Bethany M. Windsor, Karan R. Soni, Jayme R. McReynolds, Daniel S. Wheeler, John R. Mantsch, and Robert A. Wheeler
Prelimbic Prefrontal Cortical Encoding of Reward Predictive Cues, Mitchell Spring, Karan R. Soni, Daniel S. Wheeler, and Robert A. Wheeler
Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility, Ying Wang, Qian Shi, Minghui Li, Meimi Zhao, Raghavender Reddy Gopireddy, Jian-Peng Teoh, Bing Xu, Chaoqun Zhu, Kyle E. Ireton, Sanghavi Srinivasan, Shaoliang Chen, Paul J. Gasser, Julie Bossuyt, Johannes W. Hell, Donald M. Bers, and Yang K. Xiang
Submissions from 2020
Circuit development in the master clock network of mammals, Vania Carmonia-Alcocer, Kayla Rohr, Deborah A.M. Joye, and Jennifer A. Evans
Sex, Stress, and Prefrontal Cortex: Influence of Biological Sex on Stress-Promoted Cocaine Seeking, Elizabeth M. Doncheck, Gage T. Liddiard, Chaz D. Konrath, Xiaojie Liu, Laikang Yu, Luke A. Urbanik, Matthew R. Herbst, Margot C. DeBaker, Nicholas J. Raddatz, Erik C. Van Newenhizen, Jacob Mathy, Marieke R. Gilmartin, Qing-Song Liu, Cecilia J. Hillard, and John Mantsch
Organic Cation Transporter 3 and the Dopamine Transporter Differentially Regulate Catecholamine Uptake in the Basolateral Amygdala and Nucleus Accumbens, Katherine M. Holleran, Jamie H. Rose, Steven C. Fordahl, Kelsey C. Benton, Kayla E. Rohr, Paul J. Gasser, and Sara R. Jones
Acute Blockade of PACAP-Dependent Activity in the Ventromedial Nucleus of the Hypothalamus Disrupts Leptin-Induced Behavioral and Molecular Changes in Rats, Matthew M. Hurley, Eden M. Anderson, Christopher Chen, Brian Maunze, Evan Michael Hess, Megan E. Block, Neerali Patel, Zane Cooper, Riley McCoy, Tanya Dabra, William Conley, Michael J. Reilly, Matthew C. Hearing, and Sujean Choi
Marking Time: Colorful New Insights into Master Clock Circuits, Deborah A.M. Joye and Jennifer A. Evans
Reduced VIP Expression Affects Circadian Clock Function in VIP-IRES-CRE Mice (JAX 010908), Deborah A.M. Joye, Kayla Rohr, Danielle Keller, Thomas Inda, Adam Telega, Harshida Pancholi, Vania Carmonia-Alcocer, and Jennifer A. Evans
Prelimbic Input to Basolateral Amygdala Facilitates the Acquisition of Trace Cued Fear Memory Under Weak Training Conditions, Adam Kirry, Robert C. Twining, and Marieke R. Gilmartin
Predictors of In-Hospital Mortality Among Under-Five Children with Severe Acute Malnutrition in South-Western Uganda, Timothy Nduhukire, Daniel Atwine, Luwaga Rachel, and Joseph Byonanebye
Neurotoxicity of Isomers of the Environmental Toxin L-BMAA, Thomas Schneider, Catherine Simpson, Prachi Desai, Madeleine Tucker, and Doug Lobner
Submissions from 2019
Enhancing Cell Seeding and Osteogenesis of MSCs on 3D Printed Scaffolds Through Injectable BMP2 Immobilized ECM-Mimetic Gel, Farahnaz Fahimipour, Erfan Dashtimoghadam, Mohammad Mahdi Hasani-Sadrabadi, Jessica Vargas, Daryoosh Vashaee, Doug Lobner, Tahereh S. Jafarzadeh Kashi, Behnam Ghasemzadeh, and Lobat Tayebi
Roles for the Uptake2 Transporter OCT3 in Regulation of Dopaminergic Neurotransmission and Behavior, Paul J. Gasser
Prefrontal-Accumbens Opioid Plasticity: Implications for Relapse and Dependence, Matthew C. Hearing
Determinants of Occupational Injuries Among Building Construction Workers in Kampala City, Uganda, Arthur Kiconco, nathan Ruhinda, Abdullah Ali Halage, Stephen Watya, William Bazeyo, John C. Ssempebwa, and Joseph Byonanebye
Mice, Acorns, and Lyme Disease: a Case Study to Teach the Ecology of Emerging Infectious Diseases, Laurieann Klockow
Seasonal Plasticity in GABAA Signaling is Necessary for Restoring Phase Synchrony in the Master Circadian Clock Network, Kayla Rohr, Harshida Pancholi, Shabi Haider, Christopher Karow, David Modert, Nicholas J. Raddatz, and Jennifer A. Evans
Circuit-Specific Control of The Medial Entorhinal Inputs to The Dentate Gyrus by Atypical Presynaptic NMDARs Activated by Astrocytes, Iaroslav Savtchouk, Maria Amalia Di Castro, Rugina Ali, Hiltrud Stubbe, Rafael Lujan, and Andrea Volterra
Effects of Dental Composite Resin Monomers on Dental Pulp Cells, Thomas R. Schneider, Roxan Hakami-Tafreshi, Alexandra Tomasino-Perez, Lobat Tayebi, and Doug Lobner
Positions in the N‐methyl‐D‐aspartate Receptor GluN2C Subunit M3 and M4 Domains Regulate Alcohol Sensitivity and Receptor Kinetics, Man Wu, Priya Katti, Yulin Zhao, and Robert W. Peoples
Submissions from 2018
Transport of BMAA into Neurons and Astrocytes by System xc-, Rebecca Albano and Doug Lobner
17β-Estradiol Potentiates the Reinstatement of Cocaine Seeking in Female Rats: Role of the Prelimbic Prefrontal Cortex and Cannabinoid Type-1 Receptors, Elizabeth M. Doncheck, Luke A. Urbanik, Margot C. DeBaker, Laura M. Barron, Gage T. Liddiard, Jennifer J. Tuscher, Karyn M. Frick, Cecilia J. Hillard, and John Mantsch
Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior, Paul J. Gasser and Christopher A. Lowry
The Opiod Epidemic: Clinical Dental Update, Matthew Hearing
Endogenous Dopamine and Endocannabinoid Signaling Mediate Cocaine-Induced Reversal of AMPAR Synaptic Potentiation in the Nucleus Accumbens Shell, Anna E. Ingebretson, Matthew C. Hearing, Ethan D. Huffington, and Mark J. Thomas
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats, Adam J. Kirry, Matthew R. Herbst, Sarah E. Poirier, Michelle M. Maskeri, Amy C. Rothwell, Robert C. Twining, and Marieke R. Gilmartin
Kappa Counterconditioning of Cocaine Cues, John R. Mantsch and Robert C. Twining
What does the Fos say? Using Fos-based approaches to understand the contribution of stress to substance use disorders, Jayme R. McReynolds, John P. Christianson, Jordan M. Blacktop, and John Mantsch
Developmental Chromatin Restriction of Pro‐Growth Gene Networks Acts as an Epigenetic Barrier to Axon Regeneration in Cortical Neurons, Ishwariya Venkatesh, Vatsal Mehra, Zimei Wang, Ben Califf, and Murray G. Blackmore
Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction, Zimei Wang, Brian Maunze, Yunfang Wang, Pantelis Tsoulfas, and Murray G. Blackmore
KLF6 and STAT3 Co-Occupy Regulatory DNA and Functionally Synergize to Promote Axon Growth in CNS Neurons, Zimei Wang, Vatsal Mehra, Matthew T. Simpson, Brian Maunze, Dan C. Eastwood, Lyndsey Holan, Murray G. Blackmore, and Ishwariya Venkatesh
Submissions from 2017
Immunohistochemical Analysis of IL-1 beta in the Discs of Patients with Temporomandibular Joint Dysfunction, Luis Eduardo Almeida, Sean Pierce, Joseph Zacharias, William E. Cullinan, Lucia Noronha, Marcia Olandoski, Vinicius Tramontina, Carla Loreto, and Rosalia Leonardi
The Application of CRISPR Technology to High Content Screening in Primary Neurons, Ben L. Callif, Brian Maunze, Nick L. Krueger, Matthew T. Simpson, and Murray G. Blackmore
Long Days Enhance Recognition Memory and Increase Insulin-like Growth Factor 2 in the Hippocampus, Adriano Dellapolla, Ian Kloehn, Harshida Pancholi, Ben L. Callif, David Wertz, Kayla Rohr, Matthew M. Hurley, Kimberly Baker, Samer Hattar, Marieke R. Gilmartin, and Jennifer A. Evans
Role of Membrane GM1 on Early Neuronal Membrane Actions of Aβ During Onset of Alzheimer's Disease, E. J. Fernandez-Perez, Fernando Sepulveda, Robert W. Peoples, and Luis G. Aguayo
Editorial for the Special Issue: Monoamine Transporters in Health and Disease, Paul J. Gasser and Lynette C. Daws
Extending the Family: Roles for Uptake2 Transporters in Regulation of Monoaminergic Signaling, Paul J. Gasser and Lynette C. Daws
Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice, Paul J. Gasser, Matthew M. Hurley, June Chan, and Virginia M. Pickel
Circadian Waveform and Its Significance for Clock Organization and Plasticity, M. R. Gorman, Elizabeth M. Harrison, and Jennifer A. Evans
Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3, Jayme R. McReynolds, Analisa Taylor, Oliver Vranjkovic, Terra Ambrosius, Olivia Derricks, Brittany Nino, Beliz Kurtoglu, Robert A. Wheeler, David A. Baker, Paul J. Gasser, and John R. Mantsch
Analysis of BMAA Enantiomers in Cycads, Cyanobacteria, and Mammals: in vivo Formation and Toxicity of ᴅ-BMAA, J. S. Metcalf, Doug Lobner, Sandra Anne Banack, Gregory A. Cox, Peter B. Nunn, Peter B. Wyatt, and Paul Alan Cox
Combined Chondroitinase and KLF7 Expression Reduce Net Retraction of Sensory and CST Axons from Sites of Spinal Injury, Zimei Wang, Kristen N. Winsor, Evan Hess, Murray G. Blackmore, and Christopher Nienhaus
Corticosterone Regulates Both Naturally Occurring and Cocaine‐Induced Dopamine Signaling by Selectively Decreasing Dopamine Uptake, Daniel S. Wheeler, Amanda L. Ebben, Beliz Kurtoglu, Marissa E. Lovell, Austin T. Bohn, Isabella A. Jasek, David A. Baker, John R. Mantsch, Paul J. Gasser, and Robert A. Wheeler
Submissions from 2016
Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in rats, Jordan M. Blacktop, Oliver Vranjkovic, Matthieu Mayer, Matthew Van Hoof, David A. Baker, and John R. Mantsch
The Neural Encoding of Cocaine-Induced Devaluation in The Ventral Pallidum, Chung-Lung Chan, Daniel S. Wheeler, and Robert A. Wheeler
Collective Timekeeping Among Cells of the Master Circadian Clock, Jennifer A. Evans
In Synch but Not in Step: Circadian Clock Circuits Regulating Plasticity in Daily Rhythms, Jennifer A. Evans and M. R. Gorman
The Suprachiasmatic Nucleus and the Circadian Timekeeping System of the Body, Jennifer A. Evans and Rae Silver
Pituitary Adenylate-Cyclase Activating Polypeptide Regulates Hunger- and Palatability-Induced Binge Eating, Matthew M. Hurley, Brian Maunze, Megan E. Block, Michael J. Reilly, Eugene Kim, Yao Chen, Yan Li, David A. Baker, Qing-Song Liu, and Sujean Choi
N-acetylcysteine Decreases Binge Eating in a Rodent Model, M. M. Hurley, Jon M. Resch, Brian Maunze, M. M. Frenkel, David A. Baker, and Sujean Choi
Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord, Naveen Jayaprakash, Zimei Wang, Brian Hoeynck, Nicholas Krueger, Audra A. Kramer, Eric Balle, Daniel S. Wheeler, Robert A. Wheeler, and Murray G. Blackmore
Pituitary Adenylate Cyclase-Activating Polypeptide Orchestrates Neuronal Regulation Of The Astrocytic Glutamate-Releasing Mechanism System xc−, Linghai Kong, Rebecca Albano, Aric Madayag, Nicholas Raddatz, John R. Mantsch, Sujean Choi, Doug Lobner, and David A. Baker
Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress, John R. Mantsch, David A. Baker, Douglas Funk, Anh D. Lê, and Yavin Shaham
CB1 Receptor Antagonism Blocks Stress-Potentiated Reinstatement of Cocaine Seeking in Rats, Jayme R. McReynolds, Elizabeth M. Doncheck, Oliver Vranjkovic, Geoffrey S. Ganzman, David A. Baker, Cecilia J. Hillard, and John R. Mantsch
Intersubunit Interactions at Putative Sites of Ethanol Action in the M3 and M4 Domains of the NMDA Receptor GluN1 and GluN2B Subunits, Robert W. Peoples, Hong Ren, and Yulin Zhao
The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation, Christian Peters, Fernando J. Sepúlveda, Eduardo Fernández-Pérez, Robert W. Peoples, and Luis G. Aguayo
Selecting Optimal Combinations of Transcription Factors to Promote Axon Regeneration: Why Mechanisms Matter, Ishwariya Venkatesh and Murray G. Blackmore
Epigenetic Profiling Reveals a Developmental Decrease in Promoter Accessibility During Cortical Maturation in vivo, Ishwariya Venkatesh, Matthew T. Simpson, Denise M. Coley, and Murray G. Blackmore
Submissions from 2015
Regulation of System xc- by Pharmacological Manipulation of Cellular Thiols, Rebecca Albano, Nicholas J. Raddatz, Julie Hjelmhaug, David Baker, and Doug Lobner
A New Obesity Model Reveals the Hypophagic Properties of PACAP Involve the Regulation of Homeostatic Feeding in the Ventromedial Hypothalamic Nucleus and Hedonic Feeding in the Nucleus Accumbens, Matthew M. Hurley, Brian Maunze, Jon M. Resch, Mogen M. Frenkel, M. J. Reilley, Megan E. Block, David A. Baker, and Sujean Choi
PACAP and Cocaine Reinstatement: A Neuropeptide Expressed by Corticostriatal Neurons that Regulates Nucleus Accumbens Astrocytes, Linghai Kong, E. Hess, Brian Maunze, Matthew M. Hurley, Khadijah Makky, Sujean Choi, John R. Mantsch, and David A. Baker
Expression Patterns of BDNF with Central Anorexigenic Signaling Pathways Involving PACAP in the Hypothalamic Ventromedial Nuclei, Brian Maunze, Matthew M. Hurley, Jon M. Resch, M. J. Reilley, E. M. Wassmann, and Sujean Choi
Overexpression of Sox11 Promotes Corticospinal Tract Regeneration after Spinal Injury While Interfering with Functional Recovery, Zimei Wang, Ashley Reynolds, Adam Kirry, Christopher Nienhaus, and Murray G. Blackmore
Drug Predictive Cues Activate Aversion-Sensitive Striatal Neurons That Encode Drug Seeking, Daniel S. Wheeler, Mykel A. Robble, Emily M. Hebron, Matthew J. Dupont, Amanda L. Ebben, and Robert A. Wheeler
Submissions from 2014
Smooth Muscle-Protein Translocation and Tissue Function, Thomas J. Eddinger
FGF-2 Induces Neuronal Death through Upregulation of System xc-, Xiaoqian Liu, Rebecca Albano, and Doug Lobner
Time Course of Cocaine-Induced Behavioral and Neurochemical Plasticity, Victoria Lutgen, Linghai Kong, Kristen S. Kau, Aric Madayag, John Mantsch, and David A. Baker
Behavioral Assessment of Acute Inhibition of System xc - in rats, Victoria Lutgen, Jon M. Resch, Krista Qualmann, Nicholas J. Raddatz, Cristina Panhans, Ellen M. Olander, Linghai Kong, Sujean Choi, John R. Mantsch, and David A. Baker
Neurobiological Mechanisms That Contribute to Stress-related Cocaine Use, John R. Mantsch, Oliver Vranjkovic, Robert C. Twining, Paul J. Gasser, Jayme R. McReynolds, and Jordan M. Blacktop
Phosphate and Acidosis Act Synergistically to Depress Peak Power in Rat Muscle Fibers, Cassandra R. Nelson, Edward P. Debold, and Robert H. Fitts
Augmented Cystine–Glutamate Exchange by Pituitary Adenylate Cyclase-activating Polypeptide Signaling via the VPAC1 Receptor, Jon M. Resch, Rebecca Albano, Xiaoqian Liu, Julie Hjelmhaug, Doug Lobner, David A. Baker, and Sujean Choi
Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors, Jon M. Resch, Brian Maunze, Kailynn A. Phillips, and Sujean Choi
Nature of the Neurotoxic Membrane Actions of Amyloid-β on Hippocampal Neurons in Alzheimer's Disease, Fernando J. Sepúlveda, Humberto Fierro, Eduardo Fernandez, Carolina Castillo, Robert W. Peoples, Carlos Opazo, and Luis G. Aguayo
Stress-Induced Cocaine Seeking Requires a Beta-2 Adrenergic Receptor-Regulated Pathway from the Ventral Bed Nucleus of the Stria Terminalis That Regulates CRF Actions in the Ventral Tegmental Area, Oliver Vranjkovic, Paul J. Gasser, Clayton H. Gerndt, David A. Baker, and John R. Mantsch
Cyclic Ovarian Hormone Modulation of Supraspinal Δ9-tetrahydrocannabinol-induced Antinociception and Cannabinoid Receptor Binding in the Female Rat, Alexa A. Wakley, Alisha A. McBride, Linda K. Vaughn, and Rebecca M. Craft
Submissions from 2013
Environmental Circadian Disruption Elevates the IL-6 Response to Lipopolysaccharide in Blood, Kandis L. Adams, Oscar Castanon-Cervantes, Jennifer A. Evans, and Alec J. Davidson
Primary Blast Traumatic Brain Injury in the Rat: Relating Diffusion Tensor Imaging and Behavior, Matthew D. Budde, Alok Shah, Michael McCrea, William E. Cullinan, Frank A. Pintar, and Brian D. Stemper
Oral Branched-Chain Amino Acid Supplements That Reduce Brain Serotonin During Exercise in Rats Also Lower Brain Catecholamines, Sujean Choi, Briana DiSilvio, Madelyn H. Fernstrom, and John D. Fernstrom
Suprachiasmatic Astrocytes Modulate the Circadian Clock in Response to TNF-α, Jennifer A. Evans
Health Consequences of Circadian Disruption in Humans and Animal Models, Jennifer A. Evans and Alec J. Davidson
NR2A- and NR2B-containing NMDA Receptors in the Prelimbic Medial Prefrontal Cortex Differentially Mediate Trace, Delay, and Contextual Fear Conditioning, Marieke R. Gilmartin, Janine L. Kwapis, and Fred J. Helmstetter
Prefrontal Activity Links Nonoverlapping Events in Memory, Marieke R. Gilmartin, Hiroyuki Miyawaki, Fred J. Helmstetter, and Kamran Diba
Corticosterone Acts in the Nucleus Accumbens to Enhance Dopamine Signaling and Potentiate Reinstatement of Cocaine Seeking, Evan N. Graf, Robert A. Wheeler, David A. Baker, Amanda L. Ebben, Jonathan E. Hill, Jayme R. McReynolds, Mykel A. Robble, Daniel S. Wheeler, John Mantsch, and Paul J. Gasser
The HIV-1 Protein Vpr Targets the Endoribonuclease Dicer for Proteasomal Degradation to Boost Macrophage Infection, Laurieann Klockow, Hamayun J. Sharifi, Xiaoyun Wen, Meg Flagg, Andrea K.M. Furuya, Michael Nekorchuk, and Carlos M.C. de Noronha
Conserved Extracellular Cysteines Differentially Regulate the Potentiation Produced by Zn2+ in Rat P2X4 Receptors, Chao-Ying Li, Ke-Ming Xiong, Yu-Xiang Wu, Yu-Wei Liu, Lin Chen, Randall B. Stewart, Robert Peoples, and Chu-Li Yi
Reduction in Phencyclidine Induced Sensorimotor Gating Deficits in the Rat Following Increased System Xc − Activity in the Medial Prefrontal Cortex, Victoria Lutgen, Krista Qualmann, Jon M. Resch, Linghai Kong, Sujean Choi, and David A. Baker
Evidence for Covalent Linkage Between Some Plasma α2-Antiplasmin Molecules and Aα Chains of Circulating Fibrinogen, Michael W. Mosesson, Trudy Holyst, Irene Hernandez, and Kevin R. Siebenlist
A Novel Alcohol-Sensitive Position in the M3 Domain of the NMDA Receptor GluN2B Subunit, Robert W. Peoples
Intrahypothalamic Pituitary Adenylate Cyclase-activating Polypeptide Regulates Energy Balance via Site-specific Actions on Feeding and Metabolism, Jon Resch, Brian Maunze, Adriana K. Gerhardt, Samuel K. Magnuson, Kailynn A. Phillips, and Sujean Choi