A General Method for the Isolation of Pyrimidine-Bound Sugars, and Its Utilization in Studying the Conversion of Pyrimidine Ribonucleotides to Pyrimidine Deoxyribonucleotides in Rat Tissue

Author

John Carl Schultz, Marquette University

Date of Award

4-1967

Degree Type

Master's Essay - Restricted

Degree Name

Master of Science (MS)

Department

Medical

First Advisor

Paul M. Roll

Second Advisor

John R. Vercellott

Abstract

The purpose of the thesis was to investigate, in vitro, the manner of conversion of pyrimidine ribonucleotides into deoxyribonucleic acid with the possibility that an alternate pathway differing from direct reduction of the ribonucleotide(side) to the deoxyribonucleotide(side), that is without cleavage of the N-glycosidic linkage, exists . in rat tissue. In studying this problem a procedure had to be worked out for the isolation of the pyrimidine-bound sugar with almost quantitative recovery of the sugar from micromole quantities of nucleotide.

Comments

A Thesis submitted to the Faculty of the Graduate School, Marquette University in Partial Fulfillment of the Requirements for the Degree of Master of Science, Milwaukee, Wisconsin

Recommended Citation

Schultz, John Carl, "A General Method for the Isolation of Pyrimidine-Bound Sugars, and Its Utilization in Studying the Conversion of Pyrimidine Ribonucleotides to Pyrimidine Deoxyribonucleotides in Rat Tissue" (1967). Master's Essays (1922 - ). 2974.
https://epublications.marquette.edu/essays/2974